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Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones

✍ Scribed by K G Sutton; D J Martin; R D Pinnock; K Lee; R H Scott

Book ID
110006042
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
234 KB
Volume
135
Category
Article
ISSN
0007-1188

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Changes of calcium currents with intracellular pH (pHi) were investigated in chick dorsal root ganglion (DRG) neurones. High-threshold calcium currents decreased after extracellular application of a permeable weak acid, sodium acetate (CH3COONa), and increased when applying a permeable weak base, am