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GABAA receptor antagonists enhance cortical acetylcholine release induced by 5-HT3 receptor blockade in freely moving rats

✍ Scribed by Mónica Diez-Ariza; Mónica Garcı́a-Alloza; Berta Lasheras; Joaquı́n Del Rı́o; Marı́a-Javier Ramı́rez


Book ID
113998636
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
215 KB
Volume
956
Category
Article
ISSN
0006-8993

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Serotonin, (5-HT3) receptors are found in high density in the mesocorticolimbic dopamine (DA) system (Kilpatrick et al., 1987). It has been suggested that 5-HT3 antagonists inhibit mesolimbic portions of this DA system involved in brain-stimulation reward and drug-induced reward, and that this inhib