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GABAA and GABAB receptor sites involvement in rat thermoregulation

✍ Scribed by Zarrindast, M.R.; Oveissi, Y.

Book ID
123117075
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
336 KB
Volume
19
Category
Article
ISSN
0306-3623

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The effect of several ligands and Ca2+ ions on [3H]GABA binding to bovine adrenal medulla membranes was investigated. Without any blockade, the [3H]GABA bmding showed two components, one of low affinity (Kd = 139 2 22nMandB,, = 3.2 f 0.4pmoYmgprotein) and the other of high affinity (Kd = 41 2 6 nM a