✦ LIBER ✦
GABA involvement in memory consolidation: Evidence from posttrial amino-oxyacetic acid
✍ Scribed by R. J. Katz; L. Liebler
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 274 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
✦ Synopsis
In order to assess the possible effects of central GABA activation on the consolidation of shock avoidance, the GABA-T inhibitor amino-oxyacetic acid (AOAA) was administered posttrial to adult male rats. Learning was assessed over nine widely spaced sessions of 20 trials each. AOAA-treated animals showed learning within sessions and a lack of consolidation across sessions. Controls, on the other hand, showed learning both within and across sessions. This evidence agrees with previous reports suggesting GABA involvement in memory processes.