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GABA-Dopamine Receptor-Receptor Interactions in Neostriatal Membranes of the Rat

✍ Scribed by M. Pérez de la Mora; S. Ferré; K. Fuxe


Book ID
110420011
Publisher
Springer
Year
1997
Tongue
English
Weight
371 KB
Volume
22
Category
Article
ISSN
0364-3190

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Using [3H]-dopamine (DA) as the ligand of choice, we have shown that rat lymphocytes possess DA binding sites. The binding of r3H]-DA was specific, saturable, and of high affinity. The specific binding in membranes obtained from Con A-activated lymphoblasts was greater than the binding in respective