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GABA binding in mammalian brain: Inhibition by endogenous GABA

✍ Scribed by C. Napias; M.O. Bergman; P.C. Van Ness; D.V. Greenlee; R.W. Olsen


Book ID
118939521
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
627 KB
Volume
27
Category
Article
ISSN
0024-3205

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## Abstract Vigabatrin and gabaculine, both highly specific inhibitors of GABA (γ‐aminobutyric acid) transaminase, cause significant elevation of endogenous GABA levels in brain. The time course of GABA concentration after acute GABA transaminase inhibition was measured quantitatively in the α‐chlo