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G1 checkpoint protein and p53 abnormalities occur in most invasive transitional cell carcinomas of the urinary bladder

✍ Scribed by Niehans, G A; Kratzke, R A; Froberg, M K; Aeppli, D M; Nguyen, P L; Geradts, J

Book ID: 110002648
Publisher: Nature Publishing Group
Year: 1999
Tongue: English
Weight: 747 KB
Volume: 80
Category: Article
ISSN: 0007-0920
DOI: 10.1038/sj.bjc.6990483

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Seventy-nine transitional cell carcinomas (TCCs) of the urinary bladder (25 grade 1, 22 grade 2, and 32 grade 3 tumours) were examined for p53 overexpression by immunohistochemistry with a monoclonal antibody and for human papillomavirus (HPV) infection by the polymerase chain reaction (PCR). Positi