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G to A substitution in the distal CCAAT box of the Aγ-globin gene in Greek hereditary persistence of fetal haemoglobin

✍ Scribed by Gelinas, Richard; Endlich, Brian; Pfeiffer, Carla; Yagi, Mayumi; Stamatoyannopoulos, George


Book ID
109737892
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
388 KB
Volume
313
Category
Article
ISSN
0028-0836

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Some types of nondeletional heterocellular hereditary persistence of fetal hemoglobin (HPFH) appear to be caused by mutations in the beta globin gene cluster near the gamma globin genes, while in other cases the condition is associated with a gene or genes outside the beta globin gene complex. We ha