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G protein-dependent activation of a phosphoinositide-specific phospholipase C in UMR-106 osteosarcoma cell membranes

✍ Scribed by Michael Babich; Kathleen L. King; Robert A. Nissenson


Book ID
112118443
Publisher
American Society for Bone and Mineral Research
Year
2009
Tongue
English
Weight
631 KB
Volume
4
Category
Article
ISSN
0884-0431

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The role(s) of protein kinases in the regulation of G protein-dependent activation of phosphatidylinositolspecific phospholipase C by tumor necrosis factor-alpha was investigated in the osteoblast cell line MC3T3-E1. We have previously reported the stimulatory effects of tumor necrosis factor-alpha