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G-protein coupled receptors mediating long chain fatty acid signalling in the pancreatic beta-cell

โœ Scribed by Noel G. Morgan; Shalinee Dhayal


Book ID
113488978
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
321 KB
Volume
78
Category
Article
ISSN
0006-2952

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Gpbar1 (TGR5), a membrane-bound bile acid receptor, is well known for its roles in regulation of energy homeostasis and glucose metabolism. TGR5 also displays strong attenuation of macrophage reactivity in vitro, but the physiological roles of TGR5 in inflammatory response, and its mechanism, is unk