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G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

✍ Scribed by Mesri, Enrique A.; Bais, Carlos; Santomasso, Bianca; Coso, Omar; Arvanitakis, Leandros; Raaka, Elizabeth Geras; Gutkind, J. Silvio; Asch, Adam S.; Cesarman, Ethel; Gerhengorn, Marvin C.


Book ID
109761565
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
629 KB
Volume
391
Category
Article
ISSN
0028-0836

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## Abstract Tumor viruses can induce cell transformation by overcoming cellular defense mechanisms and promoting the ungoverned proliferation of infected cells. To this end, functionally related viral oncogenes have evolved in disparate viruses to over‐ride key proliferative and survival intracellu