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G-protein coupled and ITAM receptor regulation of the formin FHOD1 through Rho Kinase in platelets

โœ Scribed by S. G. THOMAS; S. D. J. CALAMINUS; L. M. MACHESKY; A. S. ALBERTS; S. P. WATSON


Book ID
109154783
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
192 KB
Volume
9
Category
Article
ISSN
1538-7933

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Gpbar1 (TGR5), a membrane-bound bile acid receptor, is well known for its roles in regulation of energy homeostasis and glucose metabolism. TGR5 also displays strong attenuation of macrophage reactivity in vitro, but the physiological roles of TGR5 in inflammatory response, and its mechanism, is unk