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G-banding and fish show loss of chromosome 10 is a frequent finding in metastatic melanoma

✍ Scribed by F.H. Thompson; Sharon Olson; Jin-Ming Yang; Y. Liu; J. Emerson; J.M. Trent; M. Nelson; R. Taetle


Book ID
113253899
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
152 KB
Volume
84
Category
Article
ISSN
0165-4608

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## Abstract We examined 11 prostate cancer xenografts and 4 cell lines for chromosome 10 alterations. Conventional comparative genomic hybridization (CGH) and array‐based CGH revealed a pattern of loss of distal 10p, gain of proximal 10p and 10q, and loss of distal 10q. In addition, array CGH ident