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Future directions of mammalian target of rapamycin (mTOR) inhibitor therapy in renal cell carcinoma

✍ Scribed by Sumanta Kumar Pal; Robert A. Figlin

Book ID: 107384410
Publisher: Springer-Verlag
Year: 2011
Tongue: English
Weight: 323 KB
Volume: 6
Category: Article
ISSN: 1776-2596
DOI: 10.1007/s11523-011-0172-y

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## Abstract ## BACKGROUND. The mammalian target of rapamycin (mTOR) pathway is up‐regulated in many human cancers, and agents targeting the mTOR pathway are in various stages of clinical development. The goal of the study was to evaluate the potential and limitations of targeting the mTOR pathway