Use of a yeast assay to detect functiona
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deVere White, Ralph W.; Deitch, Arline D.; Gumerlock, Paul H.; Shi, Xu-Bao
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Article
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1999
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John Wiley and Sons
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English
β 188 KB
## BACKGROUND. While many studies have suggested that p53 mutations are common in human cancers, the functional activity of these mutant alleles has not yet been fully addressed. We believe that information about the functional status of individual p53 mutants will prove to be important for a bette