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Fusion of the Tumor-Suppressor Gene CHEK2 and the Gene for the Regulatory Subunit B of Protein Phosphatase 2 PPP2R2A in Childhood Teratoma

✍ Scribed by Jin, Yuesheng; Mertens, Fredrik; Kullendorff, Carl-Magnus; Panagopoulos, loannis


Book ID
122762381
Publisher
Neoplasia Press
Year
2006
Tongue
English
Weight
345 KB
Volume
8
Category
Article
ISSN
1522-8002

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## Abstract A recent candidate gene association study identified a single nucleotide polymorphism (SNP) in the __PPP2R2B__ gene (rs319217, A/G) that manifests allelic differences in the cellular responses to treatment with chemotherapeutic agents (Vazquez et al., Nat Rev Drug Discov 2008;7:979‐87).