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Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

✍ Scribed by Crozat, Anne; Åman, Pierre; Mandahl, Nils; Ron, David

Book ID: 109784422
Publisher: Nature Publishing Group
Year: 1993
Tongue: English
Weight: 714 KB
Volume: 363
Category: Article
ISSN: 0028-0836
DOI: 10.1038/363640a0

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Southern blot analyses revealed a rearrangement of the EWS gene in a skeletal human myxoid chondrosarcoma. lnterphase fluorescence in sitiu hybridization (FISH) studies, using cosmid clones F7 and G9 that flank the EWS locus on 22q12, confirmed the presence of thlis EWS gene abnormality. Cloning the