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Fused polycyclic nitrogen-containing heterocycles: IX. Synthesis and molecular structure of methyl 3-(2-R-5-phenylthiazol-4-yl)-7-phenyl-7H-[1,2,4]triazolo-[3,4-b][1,3,4]thiadiazine-6-carboxylates

โœ Scribed by V. A. Mamedov; L. V. Mustakimova; A. T. Gubaidullin; I. A. Litvinov; Ya. A. Levin


Publisher
SP MAIK Nauka/Interperiodica
Year
2004
Tongue
English
Weight
364 KB
Volume
40
Category
Article
ISSN
1070-4280

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The reaction of 3-mercapto-4-aryIideneamino-l,2,4triazoles 2b-d, 3a-d with ethyl bromoacetate and/or phenacyl bromide in hot DMF and triethylamine affords the stereochemically pure 7-acyl-6-aryl-6,7dihydro-5H-lt2, 4-triazolo[3,4-b][l, 3,4]thiadiazines