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Further study on SmI2-induced reductive intramolecular cyclization: synthesis of polycyclic ethers having an angular methyl group

✍ Scribed by Keisuke Suzuki; Hiroko Matsukura; Goh Matsuo; Hiroyuki Koshino; Tadashi Nakata

Book ID: 104252347
Publisher: Elsevier Science
Year: 2002
Tongue: French
Weight: 132 KB
Volume: 43
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)02180-9

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✦ Synopsis

The SmI 2 -induced reductive intramolecular cyclization of an aldehyde and b-alkoxy acrylate was further investigated for the synthesis of polycyclic ethers having an angular methyl group. The cyclization produced 6,6-and 6,7-membered bicyclic ethers having a methyl group at C2 or C6 and C2 or C7 position, respectively.

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