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Further observations on the interactions between phenobarbital and diphenyl-hydantoin during chronic treatment in the rat

✍ Scribed by M. Rizzo; P.L. Morselli; S. Garattini


Book ID
115771356
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
401 KB
Volume
21
Category
Article
ISSN
0006-2952

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The interaction between electrically ind
✍ GΓΆran WahlstrΓΆm πŸ“‚ Article πŸ“… 1976 πŸ› Springer 🌐 English βš– 632 KB

The effect of electrically induced convulsions was tested on the tolerance to hexobarbital after chronic barbital treatment in male rats. In two experiments barbital was given in the drinking water for more than 20 weeks. The dose was around 200 mg/kg/day. Tolerance was tested with an EEG threshold