Effect of the adaptive response on the i
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Defais, Martine ;Jeggo, Penelope ;Samson, Leona ;Schendel, Paul F.
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Article
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1980
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Springer
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English
β 702 KB
The adaptive-response is an inducible repair system of E. coli which reduces the mutagenic and cytotoxic effects of alkylation damage (Samson and Cairns, 1977). In adapted cells (cells exposed to sublethal doses of alkylating agents) the induction of W-reactivation and W-mutagenesis by alkylating ag