Further observations on carcinoma in situ of the urinary bladder: Silent but extensive intraprostatic involvement
✍ Scribed by Thomas A. Seemayer; Juergen Knaack; William L. Thelmo; Nai-San Wang; M. Nisar Ahmed
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 700 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0008-543X
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✦ Synopsis
Of seven patients with carcinoma in situ of the urinary bladder in the absence of an associated papillary carcinoma, five were found to have silent but extensive intraductal prostatic involvement. In three of these the carcinoma in situ was associated with microinvasion. T h e mean age at the time of diagnosis was 68 years. All had symptoms characteristic of carcinoma in situ, including hematuria, dysuria, and urgency. I n three patients the prostatic involvement was diagnosed on transurethral resection. In two it was discovered only after radical cystectomy. T h e prostatic involvement was neither suspected clinically nor has it been previously emphasized. Although three patients are alive, apparently free of disease up to 15 months postcystectomy, two have died, one of disease. T h e importance of prostatic assessment in the evaluation of the patient with carcinoma in situ of the urinary bladder is emphasized.