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Further investigations on frequency of chromosome aberrations in bone marrow cells of Chinese hamsters after cyclophosphamide or caffeine or cyclophosphamide and caffeine treatment

✍ Scribed by G. Röhrborn; U. Buckel


Book ID
119091647
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
64 KB
Volume
38
Category
Article
ISSN
0165-1161

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The potentiating effect of caffeine (1,3,7-trimethylxanthine) on chemically induced chromosome aberrations was studied in bone marrow cells of chinese hamsters, exposed to the alkylating agent cyclophosphamide. Four experimental series were performed: In the first two tests caffeine (200 mg/kg) or c

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✍ G. Roszinsky-Köcher; G. Röhrborn 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 240 KB

The in vivo SCE formation and the induction of chromosome aberrations in the bone marrow of Chinese hamsters (Cricetulus griseus) were studied after various concentrations of cyclophosphamide, and the sensitivity of the two test methods was compared. The administraiton of 1.0, 5.0, 13.3, 25.0, and 4