𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Further investigations of circulating antibodies in colon cancer patients: On the autoantigenicity of the carcinoembryonic antigen

✍ Scribed by E. Collatz; S. von Kleist; P. Burtin

Publisher
John Wiley and Sons
Year
1971
Tongue
French
Weight
445 KB
Volume
8
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Sera from 190 patients (including 125 patients with cancer of the digestive tract) have been investigated for the presence of circulating antibodies directed against the carcinoembryonic antigen (CEA). Use of three different techniques (passive hemagglutination, immunoadsorption and immunoftuorescence) revealed no evidence for the autoantigenicity of this particular antigen. The titers demonstrated in patients' sera were due to antibodies directed against normal tissue proteins which were present in perchloric acid extracts of colonic tumors.

πŸ“œ SIMILAR VOLUMES

Circulating antibodies to p40AIS in the
Circulating antibodies to p40AIS in the sera of respiratory tract cancer patients
✍ K. Yamaguchi; M. Patturajan; B. Trink; H. Usadel; W. Koch; J. Jen; D. Sidransky πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 French βš– 81 KB πŸ‘ 1 views

Studies of immune recognition in cancer have defined several tumor antigens using autologous cytotoxic T lymphocytes and by detection of serum antibodies to tumor-associated products such as p53 and HER-2/neu. The AIS gene is a p53 homologue with multiple protein products (p40, p51, p63, p73L) on ch

Influence of spatial configuration on th
Influence of spatial configuration on the expression of carcinoembryonic antigen and mucin antigens in human bladder cancer
✍ HΓ©lΓ¨ne LaRue; Carmen Parent-Vaugeois; Alain Bergeron; Serge Champetier; and Yves πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 French βš– 137 KB πŸ‘ 2 views

CEA and cellular mucin antigens have been recognized as potential targets for specific immunotherapy and are frequently expressed in bladder cancer. We studied the coordinated expression of a bladder cancer-associated CEA glycoform and of the mucins MUC1, MUC2 and MAUB under various growth condition