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Further Insight into the Mechanism of the Irreversible Inhibition of Histidine Ammonia-Lyase by L-Cysteine and Dioxygen

✍ Scribed by Dietrich Merkel; János Rétey


Publisher
John Wiley and Sons
Year
2000
Tongue
German
Weight
226 KB
Volume
83
Category
Article
ISSN
0018-019X

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Evidence shows that Na(+)/K(+)-ATPase from kidney, brain and liver is inhibited by nitric oxide (NO) and peroxynitrite anion (ONO(2) (-)), but the mechanism is unknown. The aim of the present work was to study the inhibitory effect of NO and ONO(2) (-) on erythrocyte Na(+)/K(+)-ATPase. Erythrocyte m