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Further evidence of the role of HLA-DR4 in the genetic susceptibility to actinic prurigo

✍ Scribed by Teresa Hojyo-Tomoka; Julio Granados; Gilberto Vargas-Alarcón; Jesús K. Yamamoto-Furusho; Elisa Vega-Memije; Roberto Cortós-Franco; Octavio Flores; Fernanda Teixeira; Luciano Domínguez-Soto

Book ID
117395989
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
273 KB
Volume
36
Category
Article
ISSN
1097-6787

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HLA-DR and MT1, MT2, MT3 genotypes have been investigated in 123 Type 1 (insulin-dependent) diabetic subjects and their families. Ninety-eight percent of probands possessed either DR3 (relative risk = 5.0), or DR4 (relative risk = 6.8) or both antigens (relative risk = 14.3), emphasizing the strong