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Further evidence for non-linkage of the Hbα and Hbβ structural loci in man

✍ Scribed by S.C. Wong; T.H.J. Huisman

Book ID
115819347
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
127 KB
Volume
38
Category
Article
ISSN
0009-8981

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The linkage of Hb Valletta [α2β287(F3)Th
The linkage of Hb Valletta [α2β287(F3)Thr→Pro] and Hb F-Malta-I [α2Gγ2117(G19)His→Arg] in the Maltese population
✍ Ferdane Kutlar; Alexander E. Felice; Joseph L. Grech; William H. Bannister; Abdu 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 389 KB

We have identified a new stable abnormal hemoglobin called Hb Valletta, which is characterized by a Thr----Pro substitution at position 87 of the beta chain. This mutation was found to be linked to that of the gamma chain variant Hb F-Malta-I with a His----Arg mutation at position 117 of the G gamma