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Further evidence for genetic heterogeneity of whistling face or Freeman-Sheldon syndrome in a Chinese family

✍ Scribed by Wang, Tso-Ren ;Lin, Shio-Jean ;Opitz, John M. ;Reynolds, James F.


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
266 KB
Volume
28
Category
Article
ISSN
0148-7299

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✦ Synopsis


We report on 2 brothers with severe manifestations of the whistling-face/windmill-vane-hand syndrome (also called "craniocarpotarsal dystrophy"; Freeman-Sheldon syndrome); they were born to normal, nonconsanguineous parents. Our observations support the theory of causal heterogeneity of this syndrome and suggest existence of an autosomal or X-linked recessive form of this syndrome.