Further evidence for an antidepressant potential of the selective σ1 agonist SA 4503: electrophysiological, morphological and behavioural studies

Acute and chronic administration of the

Acute and chronic administration of the selective sigma1 receptor agonist SA4503 significantly alters the activity of midbrain dopamine neurons in rats: An in vivo electrophysiological study

✍ Yoshio Minabe; Kiyoshi Matsuno; Charles R. Ashby Jr. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 141 KB 👁 1 views

In this study, we examined the effect of the acute and repeated administration of the selective sigma () 1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride (SA4503) on the number and firing pattern of spontaneously active dopamine (DA) neurons in substantia ni