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Further consideration of phenobarbital effects on cytochrome P-450 activity in the killifish, Fundulus Heteroclitus

โœ Scribed by Adria A. Elskus; John J. Stegeman


Book ID
113379733
Publisher
Elsevier Science
Year
1989
Weight
1010 KB
Volume
92
Category
Article
ISSN
0306-4492

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Dextromethorphan (DXM) is commonly used as a probe for the metabolic activity of the debrisoquine isozyme (P-450 lID6) of the cytochrome P-450 mixed-function oxidase system. Several reports have described changes in P-450 activity with dietary alteration. This study was conducted to determine the ef