Metalated Epoxides as Carbenoids โ Furth
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Luc Dechoux; Claude Agami; Eric Doris; Charles Mioskowski
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Article
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2001
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John Wiley and Sons
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English
โ 259 KB
The intramolecular cyclopropanation of ฮฒ,ฮณ-unsaturated metalated epoxides derived from 11 yielded the highly strained tricyclic intermediates 7. The facile hydrolysis of the latter species afforded the ฮฑ-keto spirocyclopropanes 8 in a stereospecific fashion. Indeed, the stereochemistry of the