Furans in synthesis 101. An efficient construction of the bicyclo[5.3.0]decane ring system of fastigilin-C
β Scribed by Steven P Tanis; Mark C McMills; Terrence A Scahill; David A Kloosterman
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 308 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
The efficient preparation of an advanced intermediate for the synthesis of Fastigiln-C 2, via a furan terminated cation& cyclkation, is descrbd.
π SIMILAR VOLUMES
An efficient strategy for the rapid construction of the guiane bicyclo[5.3.0]decane ring system from appropriately substituted 4-alkyn-1-ols has been developed. This methodology relies on a MeLi-catalyzed tandem 5-exo-dig cyclization/Claisen rearrangement sequence as the key ring forming step.
An enantioselective method to prepare trans-fused bicyclo[5.3.0]decane systems is described. This methodology is based on two key reactions: a [4Ο©3] cycloaddition reaction (to generate the seven-membered ring) and the Nicholas reaction (to insert the five-membered ring). The application of this meth
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v