Furan ring opening—indole ring closure: a new modification of the Reissert reaction for indole synthesis
✍ Scribed by Alexander V Butin; Tat‘yana A Stroganova; Irina V Lodina; Gennady D Krapivin
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 90 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
A new modification of the Reissert reaction is reported. On treatment of 2-tosylaminobenzylfurans with ethanolic HCl, some indole derivatives have been obtained. The furan ring served as the origin of a carbonyl group in this reaction.
📜 SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
## Abstract magnified image A new synthetic approach to furo[2′,3′:3,4]cyclohepta[1,2‐__b__]indolium chlorides is elaborated starting from 2‐acetylaminoaryldifurylmethanes or 2‐aminoaryldifurylmethanes under treatment with methanolic HCl solution. The reaction proceeds in three steps: recyclizatio
## Abstract A principally new method for the synthesis of polyfunctional title compounds is developed by recyclization of 2‐[2‐(acylamino)benzyl]furans in the presence of POCl~3~.