Fungal metabolites xxii()̊: the unprecedented structure of saponaceolide a, a cytotoxic c-30 terpenoid from Tricholoma Saponaceum
✍ Scribed by Maria De Bernardi; Luigi Garlaschelli; Gluseppina Gattl; Giovanni Vidari; Paola Vita Finzi
- Book ID
- 104203136
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 399 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4020
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✦ Synopsis
The structure of saponaceolide A, a neu cytotoxic C-30 terpenoid from Tricholoma saponaceum has been established by spectroscopic methods, including single crystal X-ray analysis. Its biogenetic origin is discussed. structures of many secondary metabolites. 1.2 Moreover a large number of species are to be studied as yet. Very often the mushroom metabolites show also antifeedant, antibiotic, cytotoxic, irawnological and other biological activities. Among the several genera that make up the Tricholomataceae family,3 the genus Tricholoma (Fr.) @cl. is one of the largest and comprises also species which are considered not edible or even toxic. The most significant achievements of the few previous chemical studies on this genus are the structural determination of new pigments (i.e. 1) from T. equestre4, the finding of straight chain acetylenic compounds, such as nudic acid B (diatretyne 11) (2), in T. nudum5, and the isolation of tricholodic acid (3) from a Japanese species.6