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Fundus changes in chronic membranoproliferative glomerulonephritis type II

✍ Scribed by Brigitte Michielsen; Anita Leys; Boudewijn Damme; Luc Missotten

Publisher
Springer-Verlag
Year
1990
Tongue
English
Weight
475 KB
Volume
76
Category
Article
ISSN
0012-4486

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✦ Synopsis

Chronic membranoproliferative glomerulonephritis type II (dense deposit disease) is a renal disease characterized by dense deposits in the glomerular and tubular basement membranes. We report a retinopathy with diffuse retinal pigment alterations in 11 out of 12 patients with this disease. Four of the eleven patients also presented disciform macular detachment and choroidal neovascularisation. The lesions were observed at the earliest 1 year after the diagnosis of the renal disease. In a control group of 17 patients with chronic membranoproliferative glomerulonephritis type I none of the patients presented similar fundus lesions.

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✍ Kevin A. Kurtz; Annette J. Schlueter πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 168 KB

## Abstract Membranoproliferative glomerulonephritis type II (MPGN II) is a rare kidney disease identified microscopically by electron‐dense deposits surrounded by complement component C3 in glomerular basement membranes. MPGN II usually leads to renal failure, and patients with MPGN II experience