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Functions of unconventional myosins

✍ Scribed by Xufeng Wu; Goeh Jung; John A Hammer Jr.

Book ID: 114309650
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 124 KB
Volume: 12
Category: Article
ISSN: 0955-0674
DOI: 10.1016/s0955-0674(99)00055-1

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Mutations of the unconventional myosins genes encoding myosin VI, myosin VIIA and myosin XV cause hearing loss and thus these motor proteins perform fundamental functions in the auditory system. A null mutation in myosin VI in the congenitally deaf Snell's waltzer mice (Myo6 sv ) results in fusion o