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Functions and biosynthesis of plasmalogens in health and disease

โœ Scribed by Pedro Brites; Hans R Waterham; Ronald J.A Wanders


Book ID
116272795
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
476 KB
Volume
1636
Category
Article
ISSN
1388-1981

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## Abstract __SPG4__, the gene encoding for spastin, a member of the ATPases associated with various cellular activities (AAA) family, is mutated in around 40% of cases of autosomal dominant hereditary spastic paraplegia (ADโ€HSP). This group of neurodegenerative diseases is characterized by a progr