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Functionally diverse monofluorinated vinylic compounds from trifluoroethanol

โœ Scribed by Sunita T. Patel; Jonathan M. Percy; Robin D. Wilkes


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
231 KB
Volume
37
Category
Article
ISSN
0040-4039

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Monofluorinated allylic ether 3, synthesised in 4 steps from trifluoroethanol, underwent metallation at the CF vinylic position upon treatment with strong base. Monofluoro vinyllithium 4 was trapped efficiently with a variety of electrophiles, including Group (IV) halides, methyl iodide and benzalde