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Functionalized congeners of adenosine: preparation of analogs with high affinity for A1-adenosine receptors

โœ Scribed by Jacobson, Kenneth A.; Kirk, Kenneth L.; Padgett, William L.; Daly, John W.


Book ID
120646450
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
751 KB
Volume
28
Category
Article
ISSN
0022-2623

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Two potent qgands for adenosine receptors have been synthesized with non-exchangeable H labeling to high specific activity. Both are adenosine antagonists, one a carboxylic acid congener, 1, and the other an amino congener, 2. and are structurally related to 1 ,~-dipropyl-8-phenylxanthine. The labe