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Functionalized BINOL Derivatives as Ligands for Enantioselectively Catalyzed Aldol Additions: Highly Enantioselective Synthesis of Chiral β-Hydroxy Thioesters.

✍ Scribed by Reinhold Zimmer; Luise Schefzig; Anke Peritz; Vjekoslav Dekaris; Hans-Ulrich Reissig


Publisher
John Wiley and Sons
Year
2004
Weight
33 KB
Volume
35
Category
Article
ISSN
0931-7597

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## Abstract A new class of chiral β‐amino disulfides was synthesized from readily available and inexpensive starting materials by a straightforward method and their abilities as ligands were examined in the enantioselective addition of diethylzinc to aldehydes. Enantiomeric excesses of up to 99% ha