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Functionalized 2,5-Disubstituted Benzazepines: Stereoselective Synthesis of 3-Methyl-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-2-carbonitrile and Related Derivatives.

โœ Scribed by Jeff E. Cobb; Suganthini S. Nanthakumar; Randy Rutkowske; David E. Uehling


Publisher
John Wiley and Sons
Year
2004
Weight
21 KB
Volume
35
Category
Article
ISSN
0931-7597

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Chemistry of Functionalized Benzazepines. Part 5. Synthesis and Chemical Transformation of the 1,2,4,5-Tetrahydrospiro[3H-2benzazepine-3,1'-cycloalkanes]. -A number of new spiroderivatives of tetrahydro-2-benzazepine (III) are synthesized by reaction of imines (I) with allyl Grignard reagent (II)