✦ LIBER ✦
Functionalization of PAMAM dendrimers with nitronyl nitroxide radicals as models for the outer-sphere relaxation in dentritic potential MRI contrast agents
✍ Scribed by Giancarlo Francese; Frank A. Dunand; Claudia Loosli; André E. Merbach; Silvio Decurtins
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 164 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0749-1581
- DOI
- 10.1002/mrc.1151
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✦ Synopsis
Abstract
PAMAM dendrimers functionalized with nitronyl nitroxide radicals were characterized. Quantitative determination of substitution with radicals was performed using EPR and electrochemical methods. The study of the ^1^H NMR relaxation of the surrounding water showed how the outer‐sphere contribution to the relaxivity may be limited by the presence of the dendrimer core. Copyright © 2003 John Wiley & Sons, Ltd.