Functional variations in parenchymal microvascular systems within the brain

✍ Scribed by Joseph Fenstermacher; Hiroyuki Nakata; Atsushi Tajima; Shinn-Zong Lin; Tadahiro Otsuka; Virgil Acuff; Ling Wei; Daniel Bereczki

• Book ID: 102530664
• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: English
• Weight: 260 KB
• Volume: 19
• Category: Article
• ISSN: 0740-3194
• DOI: 10.1002/mrm.1910190205

✦ Synopsis

Variations in microvascular system functions were observed among a number of brain areas. The rates of local blood flow varied 18-fold among areas and were extremely high in neuroendocrine structures. Marked differences in blood flow were also found within some brain structures. The volume of radiolabeled blood in perfused parenchymal microvessels ranged from 5 to 70 microliters/g and correlated closely with local cerebral blood flow. The hematocrits within parenchymal microvessels were 45-75% of the arterial hematocrit, which indicates that red cells more rapidly traverse brain microvessels than do plasma proteins. The mean transit times of blood through parenchymal microvessels were extremely short and ranged from 0.3 to 0.6 s.