Functional variation in the 3′ untranslated region of the serotonin transporter in human and rhesus macaque
✍ Scribed by E. J. Vallender; C. M. Priddy; S. Hakim; H. Yang; G.-L. Chen; G. M. Miller
- Book ID
- 111273212
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 206 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1601-1848
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The human serotonin transporter (5-HTT), encoded by a single gene on chromosome 17q11.2, is expressed in brain and blood cells. 5-HTT is implicated in mood and anxiety regulation, and is where antidepressant and antianxiety drugs initially act in the brain. A 5-HTT-linked promoter region (5-HTTLPR)
## Abstract The serotonin system is an important neurophysiological mediator of many behavioral phenotypes. Genetic variation within this system is thought to contribute not only to the natural range of behavioral differences, but also to neuropsychiatric pathologies. Cognitive flexibility, the abi