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Functional variant of KLOTHO: a breast cancer risk modifier among BRCA1 mutation carriers of Ashkenazi origin

✍ Scribed by Wolf, I; Laitman, Y; Rubinek, T; Abramovitz, L; Novikov, I; Beeri, R; Kuro-O, M; Koeffler, H P; Catane, R; Freedman, L S

Book ID
109971094
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
443 KB
Volume
29
Category
Article
ISSN
0950-9232

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## Abstract Early age at first birth and multiparity have been associated with a decrease in the risk of breast cancer in women in the general population. We examined whether this relationship is also present in women at high risk of breast cancer due to the presence of a mutation in either of the