Functional Transitions Between Epileptiform-Like Activity and Associative Memory in Hippocampal Region CA3

Simulations of epileptiform activity in

Simulations of epileptiform activity in the hippocampal CA3 region in vitro

✍ Roger D. Traub; John G. R. Jefferys 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 522 KB

The hippocampus is one of the most seizure-prone regions of the central nervous system. Indeed, even in hippocampal slices, epileptiform activity can be easily induced by pharmacological blockade of GABAA receptors. The resulting activity consists of one or more synchronized population bursts that a