Nuclear translocation of UDCA by the glu
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Susana SolΓ‘; Joana D. Amaral; Rui E. Castro; Rita M. Ramalho; Pedro M. Borralho;
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Article
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2005
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John Wiley and Sons
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English
β 322 KB
Ursodeoxycholic acid (UDCA) inhibits classical mitochondrial pathways of apoptosis by either directly stabilizing mitochondrial membranes or modulating specific upstream targets. Furthermore, UDCA regulates apoptosis-related genes from transforming growth factor β€1 (TGF-β€1)-induced hepatocyte apopto