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Functional T-cell responses generated by dendritic cells expressing the early HIV-1 proteins Tat, Rev and Nef

✍ Scribed by Sabine D. Allard; Katrien Pletinckx; Karine Breckpot; Carlo Heirman; Aude Bonehill; Annelies Michiels; Carel A. van Baalen; Rob A. Gruters; Albert D.M.E. Osterhaus; Patrick Lacor; Kris Thielemans; Joeri L. Aerts

Book ID: 116960580
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 558 KB
Volume: 26
Category: Article
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2008.04.077

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## Abstract Recent studies have suggested including nonstructural proteins as Tat and Vpr in HIV vaccines. However, little is known about the CD4^+^ T‐cell response that these small proteins induce in humans. We have therefore evaluated these responses by __in vitro__ priming experiments of CD4^+^