Functional reorganization induced by endovascular embolization of a cerebral AVM
✍ Scribed by Randolph S. Marshall; Lotfi Hacein-Bey; William L. Young; John Pile-Spellman; Sam Das; Gerard Perera; J. P. Mohr
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 573 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1065-9471
No coin nor oath required. For personal study only.
✦ Synopsis
We mapped motor function in a patient with a cerebral arteriovenous malformation (AVM) before and after treatment with endovascular embolization. Functional activation using technetium-99mhexamethylpropyleneamine single photon emission tomography (99mTc-HMPAO-SPECT) demonstrated a redistribution of regional cerebral blood flow (rCBF) that correlated with clinical improvement. Intravascular feeding artery pressure measurements, serial angiography, and challenge with a pharmacological vasodilator enabled us to explore possible mechanisms of functional reorganization.