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Functional relationship between fibroblast growth factor-8 and bone morphogenetic proteins in regulating steroidogenesis by rat granulosa cells

✍ Scribed by Tomoko Miyoshi; Fumio Otsuka; Misuzu Yamashita; Kenichi Inagaki; Eri Nakamura; Naoko Tsukamoto; Masaya Takeda; Jiro Suzuki; Hirofumi Makino


Book ID
116734802
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
642 KB
Volume
325
Category
Article
ISSN
0303-7207

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Bone morphogenetic proteins (BMPs) are multifunctional regulators of proliferation, differentiation and apoptosis. BMP-6 is involved in numerous developmental processes. We have demonstrated expression of BMP-6 in breast cancer cell lines by RT-PCR and immuno-histochemistry. The level of BMP-6 mRNA